TRACKER 6 OCT 2026 · WADA publishes the 2027 Prohibited List, in force January 1, 2027. What changed
plainly graded.

PT-141

Also called "bremelanotide", "Vyleesi"
FDA approved, one useWADA: being checked
STATUS AS OF
FDA: approved as Vyleesi for hypoactive sexual desire disorder in premenopausal women only · WADA: wADA status not yet checked against the List · tracker entry

The short answer: PT-141 is the research name for bremelanotide, a melanocortin-receptor peptide. As of October 17, 2026 it is FDA-approved as Vyleesi for one use: low sexual desire in premenopausal women. Products sold online as PT-141 for other uses are not the approved drug.

Written by Maren Holt 1 PUBLIC SOURCES · UPDATED 17 OCT 2026 · NO TIES TO SELLERS
How we source

We collect and compare information from public, cited sources. We cannot guarantee that it is complete, current or correct. This is not medical advice. Only a doctor can prescribe, and a doctor should confirm anything you read here before you act on it.

Based on public sources; we cannot guarantee it is correct. Not medical advice. A doctor should prescribe and confirm. Full disclaimer

What is PT-141?

Melanocortin peptide approved for low sexual desire in some women. Full section still to be written.

What is PT-141 claimed to do, and what does the evidence show?

Overall gradeApproved
Strongest evidencePhase 3 trials
UseClaimedShownGrade
Low sexual desire in premenopausal women Raises sexual desire Approved by the FDA for this use only.[1] Approved
Low sexual desire in premenopausal womenApproved
Claimed: Raises sexual desire Shown: Approved by the FDA for this use only.[1]

What are the known risks and side effects of PT-141?

The approved label lists the known side effects and warnings. We link to it rather than restate it.

Who should be especially careful
  • People who are pregnant, trying to get pregnant or breastfeeding. There is no human data in pregnancy.
  • Anyone under 18. It has not been studied in young people.
  • Tested athletes and service members. Check with USADA or your service's rules first. A positive test counts whatever the label said.
  • People taking prescription medicines. Interactions have not been studied. Bring the product label to your clinician.
Get medical help now if you have
  • Swelling of the face, lips or throat, trouble breathing, chest pain, a racing heart or fainting. Call 911.
  • Redness spreading from an injection site, warmth, pus or a fever. Get same-day care.
  • Unsure what you took or whether a reaction is serious: Poison Control 1-800-222-1222 (free, 24 hours).
  • Thoughts of harming yourself: call or text 988.

Is PT-141 banned in sport?

WADA status not yet checked against the List. Anti-doping rules work on strict liability: a positive test counts whatever the label said.

What don't we know about PT-141?

Still unknown Still being written.
Why this page has no dosing We don't publish doses, schedules or mixing instructions for PT-141 or any unapproved peptide. No human dose has been established for most of these uses, so we list what to ask a licensed prescriber instead. Here's why, and who can legally answer

What should you tell your doctor if you're using PT-141?

Tell them exactly what you took, for how long, and where it came from, and bring the label. These questions can help the conversation:

  • Is there an approved treatment for my goal that has been tested in people?
  • What should I watch for, and which symptoms mean I should stop and call you?
  • Could it interact with the medicines I already take?
Sources
  1. DailyMed / US Food and Drug Administration. Vyleesi (bremelanotide) prescribing information .
Changelog
17 OCT 2026 Draft. Statuses read from the regulatory record dated 2026-10-17.
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